Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755351 | 0.89 | KDM1A (0.50) | KDM1ANUDT1POLBRAD52PLAU | |
| SCHEMBL9755380 | 0.89 | POLB (0.47) | KDM1AACHENUDT1POLBRAD52 | |
| SCHEMBL9755321 | 0.86 | ACHE (0.47) | KDM1AACHENPSR1ALDH1A1KMT2A | |
| SCHEMBL9755414 | 0.83 | KDM1A (0.45) | KDM1AACHEPOLBRAD52NPSR1 | |
| SCHEMBL9755399 | 0.80 | KDM1A (0.48) | KDM1AACHENPSR1KMT2ATOP2A | |
| SCHEMBL9755331 | 0.80 | ACHE (0.39) | KDM1AACHEPOLBRAD52PLAU | |
| SCHEMBL9755340 | 0.79 | ACHE (0.38) | KDM1AACHEPOLBRAD52NPSR1 | |
| SCHEMBL9755334 | 0.79 | ACHE (0.38) | KDM1AACHEPOLBRAD52NPSR1 | |
| SCHEMBL9755333 | 0.76 | KDM1A (0.51) | KDM1APOLBRAD52KMT2ATOP2A | |
| SCHEMBL9755411 | 0.74 | POLB (0.47) | KDM1AACHENUDT1POLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |