Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755402 | 0.92 | KDM1A (0.43) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755334 | 0.84 | ACHE (0.38) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755378 | 0.83 | KDM1A (0.44) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755373 | 0.82 | ACHE (0.39) | KDM1AKMT2APOLBRAD52MEN1 | |
| SCHEMBL9755355 | 0.80 | KDM1A (0.50) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755337 | 0.78 | KMT2A (0.42) | KDM1AKMT2AMEN1KDM4E | |
| SCHEMBL9755348 | 0.78 | POLB (0.42) | KDM1APOLBRAD52EGFRPDGFRB | |
| SCHEMBL9755394 | 0.78 | POLB (0.44) | KDM1APOLBRAD52EGFRPDGFRB | |
| SCHEMBL9755331 | 0.77 | ACHE (0.39) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755340 | 0.76 | ACHE (0.38) | KDM1AKMT2APOLBRAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |