Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755348 | 0.94 | POLB (0.42) | POLBRAD52NUDT1PDGFRBPDGFRA | |
| SCHEMBL9755331 | 0.86 | ACHE (0.39) | POLBRAD52MAPTACHEKDM1A | |
| SCHEMBL9755334 | 0.79 | ACHE (0.38) | POLBRAD52MAPTACHEKDM1A | |
| SCHEMBL9755340 | 0.79 | ACHE (0.38) | POLBRAD52MAPTACHEKDM1A | |
| SCHEMBL9755373 | 0.79 | ACHE (0.39) | POLBRAD52MAPTKDM4ETP53 | |
| SCHEMBL9755410 | 0.78 | KDM1A (0.41) | POLBRAD52PDGFRBPDGFRAMAPT | |
| SCHEMBL9755411 | 0.77 | POLB (0.47) | POLBRAD52NUDT1PDGFRBPDGFRA | |
| SCHEMBL9755402 | 0.73 | KDM1A (0.43) | POLBRAD52PDGFRBPDGFRAMAPT | |
| SCHEMBL9755378 | 0.73 | KDM1A (0.44) | POLBRAD52PDGFRBPDGFRAMAPT | |
| SCHEMBL9755380 | 0.73 | POLB (0.47) | POLBRAD52NUDT1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |