Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755331 | 0.93 | ACHE (0.39) | ACHEPOLBRAD52KDM1AKMT2A | |
| SCHEMBL9755373 | 0.92 | ACHE (0.39) | ACHEPOLBRAD52KDM1AKMT2A | |
| SCHEMBL9755334 | 0.92 | ACHE (0.38) | ACHEPOLBRAD52KDM1AKMT2A | |
| SCHEMBL9755378 | 0.82 | KDM1A (0.44) | POLBRAD52KDM1AKMT2AMEN1 | |
| SCHEMBL9755337 | 0.79 | KMT2A (0.42) | ACHEKDM1AKMT2AMEN1NPSR1 | |
| SCHEMBL9755348 | 0.79 | POLB (0.42) | ACHEPOLBRAD52KDM1AMAPT | |
| SCHEMBL9755394 | 0.79 | POLB (0.44) | ACHEPOLBRAD52KDM1AMAPT | |
| SCHEMBL9755414 | 0.79 | KDM1A (0.45) | ACHEPOLBRAD52KDM1AKMT2A | |
| SCHEMBL9755466 | 0.79 | KDM1A (0.42) | ACHEPOLBRAD52KDM1AKMT2A | |
| SCHEMBL9755410 | 0.76 | KDM1A (0.41) | POLBRAD52KDM1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |