Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755546 | 0.73 | POLA1 (0.35) | POLA1POLBPDE4DPDE3ASLC29A1 | |
| SCHEMBL17027931 | 0.68 | POLB (0.46) | POLA1POLBPDE4DPDE3ASLC29A1 | |
| SCHEMBL13234931 | 0.67 | POLA1 (0.44) | POLA1POLBTSHRGLAP2RY2 | |
| SCHEMBL12354843 | 0.67 | POLA1 (0.44) | POLA1POLBTSHRGLAP2RY2 | |
| SCHEMBL12363580 | 0.67 | POLA1 (0.44) | POLA1POLBTSHRGLAP2RY2 | |
| SCHEMBL17027893 | 0.67 | POLA1 (0.44) | POLA1POLBTSHRGLAP2RY2 | |
| SCHEMBL22959421 | 0.67 | LMNA (0.55) | TSHRGLAP2RY2LMNATHRB | |
| SCHEMBL4384095 | 0.67 | LMNA (0.49) | POLA1PDE4DPDE3ASLC29A1TSHR | |
| SCHEMBL17027928 | 0.67 | POLB (0.56) | POLA1POLBPDE3APOLGP2RY2 | |
| SCHEMBL845632 | 0.66 | LMNA (0.54) | PDE4DPDE3ASLC29A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019727-A1 | 5'-HYDROGENPHOSPHONATES AND 5'-METHYLPHOSPHONATES OF SUGAR MODIFIED NUCLEOSIDES, COMPOSITIONS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-12-26 | — | — | WO | disclosed |