Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220663 | 0.86 | CA1 (0.42) | KMT2AGRIK1GRIK2CPA1CA1 | |
| SCHEMBL11128664 | 0.85 | ALDH1A1 (0.43) | KMT2AGRIK1GRIK2CPA1CA1 | |
| SCHEMBL15131912 | 0.84 | GRIK1 (0.44) | KMT2AGRIK1GRIK2CPA1CA1 | |
| SCHEMBL11128669 | 0.83 | MEN1 (0.41) | KMT2AGRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL4282149 | 0.82 | GRIK1 (0.40) | GRIK1GRIK2CPA1FOLH1ABCC4 | |
| SCHEMBL9755829 | 0.81 | SLC6A2 (0.40) | KMT2AGRIK1GRIK2CPA1CA1 | |
| SCHEMBL584778 | 0.81 | KMT2A (0.53) | KMT2ACA1CA2MMEFOLH1 | |
| SCHEMBL15628064 | 0.80 | L3MBTL1 (0.38) | KMT2AGRIK1GRIK2CPA1MEN1 | |
| SCHEMBL15902765 | 0.80 | HCAR2 (0.38) | GRIK1GRIK2CPA1ALDH1A1LMNA | |
| SCHEMBL15600133 | 0.80 | CA1 (0.52) | KMT2AGRIK1GRIK2CPA1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |