Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220663 | 0.82 | CA1 (0.42) | MEN1TSHRKMT2ACA1CA2 | |
| SCHEMBL9755825 | 0.81 | KMT2A (0.40) | MEN1KMT2AFOLH1CA1CA2 | |
| SCHEMBL11332479 | 0.81 | CA1 (0.48) | SLC6A3MEN1TSHRNFKB1KMT2A | |
| SCHEMBL11323003 | 0.81 | CA1 (0.40) | MEN1TSHRKMT2ACA1CA2 | |
| SCHEMBL2136259 | 0.81 | ALDH1A1 (0.43) | MEN1TSHRKMT2ACA1CA2 | |
| SCHEMBL15131912 | 0.81 | GRIK1 (0.44) | MEN1TSHRKMT2ACA1CA2 | |
| SCHEMBL9709918 | 0.79 | CA1 (0.43) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL9732859 | 0.79 | LMNA (0.54) | TSHRKMT2ACA1CA2ALDH1A1 | |
| SCHEMBL463194 | 0.79 | FOLH1 (0.56) | SLC6A2SLC6A4BLMSLC6A3FOLH1 | |
| SCHEMBL29051932 | 0.79 | CA2 (0.65) | TSHRCA1CA2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |