SCHEMBL975593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL68469	0.83	PLA2G1B (0.60)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL14615113	0.83	ALDH1A1 (0.49)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL11624275	0.83	LMNA (0.52)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL2506707	0.82	LMNA (0.49)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL9495325	0.82	LMNA (1.00)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL2958622	0.82	MCL1 (0.61)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL25203083	0.81	ALDH1A1 (0.53)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL5425424	0.80	LMNA (0.56)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL12922067	0.79	HDAC1 (0.62)	LMNAMAPK1ALDH1A1MAPTKDM4E
	SCHEMBL9495317	0.79	LMNA (0.82)	LMNAMAPK1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.