Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756837 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL4906689 | 0.81 | MAOA (0.58) | PKMSMN1; SMN2RAB9A | |
| SCHEMBL9757027 | 0.80 | KDM4E (0.58) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL9757028 | 0.80 | KDM4E (0.58) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL5848040 | 0.77 | KDM4E (0.87) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL2136928 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL2136926 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL27833553 | 0.77 | KDM4E (0.87) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL5848038 | 0.77 | KDM4E (0.87) | ALDH1A1KDM4EPKMLMNAAKR1C3 | |
| SCHEMBL10927966 | 0.77 | KDM4E (0.78) | ALDH1A1KDM4EPKMLMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |