Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756853 | 0.81 | KMT2A (0.46) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9756828 | 0.79 | RAB9A (0.38) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9756921 | 0.78 | NFE2L2 (0.38) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3532100 | 0.76 | HDAC6 (1.00) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3532094 | 0.76 | HDAC6 (1.00) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11495341 | 0.76 | RAB9A (0.58) | HDAC8KDM4EMAPTCYP1A2HTT | |
| SCHEMBL9756852 | 0.75 | MAPT (0.48) | KDM4ELMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL9756976 | 0.72 | JUN (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9756903 | 0.72 | RAB9A (0.44) | HDAC8KDM4EMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL9756888 | 0.71 | NAMPT (0.55) | KDM4EMAPTMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |