Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495341 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9756855 | 0.79 | CES2 (0.41) | RAB9ASMN1; SMN2HDAC8NPC1ALDH1A1 | |
| SCHEMBL9756856 | 0.74 | PTPN1 (0.40) | SMN1; SMN2HDAC8ALDH1A1MEN1KMT2A | |
| SCHEMBL9756827 | 0.73 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL9756899 | 0.72 | HDAC6 (0.60) | RAB9ASMN1; SMN2HDAC8NPC1ALDH1A1 | |
| SCHEMBL9756984 | 0.72 | GAA (0.38) | RAB9ASMN1; SMN2ALDH1A1TP53KDM4E | |
| SCHEMBL9756986 | 0.70 | RAB9A (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL13715720 | 0.70 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL9756889 | 0.70 | LMNA (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL4021547 | 0.70 | MGAM (0.67) | RAB9ASMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |