Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757150 | 0.89 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757649 | 0.82 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757151 | 0.82 | NR4A2 (0.43) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757226 | 0.81 | EDNRA (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757227 | 0.81 | EDNRA (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757716 | 0.79 | ALOX5AP (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757147 | 0.75 | EDNRA (0.42) | — | |
| SCHEMBL9757209 | 0.75 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2 | |
| SCHEMBL10402152 | 0.72 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2 | |
| SCHEMBL10402153 | 0.72 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | claimed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | claimed |
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |