Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757227 | 0.90 | EDNRA (0.48) | CYSLTR1CYSLTR2EDNRAKMT2AKDM4E | |
| SCHEMBL9757226 | 0.90 | EDNRA (0.48) | CYSLTR1CYSLTR2EDNRAKMT2AKDM4E | |
| SCHEMBL9757078 | 0.89 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757716 | 0.86 | ALOX5AP (0.48) | CYSLTR1CYSLTR2EDNRASLC26A4KMT2A | |
| SCHEMBL9757147 | 0.82 | EDNRA (0.42) | EDNRASLC26A4KMT2ANPC1RAB9A | |
| SCHEMBL9757080 | 0.81 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2KMT2AKDM4ENPC1 | |
| SCHEMBL9757209 | 0.80 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9757151 | 0.76 | NR4A2 (0.43) | CYSLTR1CYSLTR2EDNRATBXAS1 | |
| SCHEMBL9757054 | 0.75 | PDE10A (0.58) | CYSLTR1CYSLTR2EDNRAALOX5AP | |
| SCHEMBL9757224 | 0.72 | EDNRA (0.48) | CYSLTR1EDNRANPC1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |