Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757622 | 0.86 | HTR7 (0.40) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9757411 | 0.79 | HTR7 (0.36) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9873403 | 0.77 | PARP1 (0.48) | — | |
| SCHEMBL9757358 | 0.76 | HTR7 (0.41) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9757172 | 0.76 | HTR7 (0.40) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9757270 | 0.75 | HTR7 (0.51) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9757507 | 0.75 | TP53 (0.35) | HTR7NPC1ALDH1A1 | |
| SCHEMBL9757401 | 0.74 | HTR1A (0.38) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9757373 | 0.72 | HTR7 (0.52) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7017660 | 0.65 | PARP1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |