Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9757172 | 0.99 | HTR7 (0.40) | HTR7KDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL9757270 | 0.82 | HTR7 (0.51) | HTR7KDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL9757373 | 0.82 | HTR7 (0.52) | HTR7KDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL9757411 | 0.81 | HTR7 (0.36) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757622 | 0.81 | HTR7 (0.40) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757237 | 0.76 | HTR1A (0.34) | HTR7HSD17B10ALDH1A1HTR1ADRD2 | |
| SCHEMBL9757366 | 0.76 | HTR7 (0.49) | HTR7 | |
| SCHEMBL9757507 | 0.76 | TP53 (0.35) | HTR7KDM4EALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL9757178 | 0.76 | HTR7 (0.48) | HTR7 | |
| SCHEMBL9726229 | 0.70 | HTR7 (0.48) | HTR7ALDH1A1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |