Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757528 | 0.86 | PARP1 (0.47) | PARP1 | |
| SCHEMBL9757450 | 0.78 | HTR7 (0.61) | — | |
| SCHEMBL9873768 | 0.78 | HTR7 (0.44) | — | |
| SCHEMBL9757173 | 0.76 | HTR7 (0.64) | — | |
| SCHEMBL9757401 | 0.76 | HTR1A (0.38) | — | |
| SCHEMBL9757366 | 0.75 | HTR7 (0.49) | — | |
| Hydrochloric Acid SCHEMBL9757178 | 0.74 | HTR7 (0.48) | — | |
| SCHEMBL9873171 | 0.73 | SIGMAR1 (0.40) | — | |
| SCHEMBL9757463 | 0.72 | HTR7 (0.63) | — | |
| SCHEMBL9757629 | 0.72 | HTR7 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |