SCHEMBL9757338

SCHEMBL9757338

O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCC(c2c[nH]c3ccccc23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757165 0.82 HTR7 (0.66)
SCHEMBL9635366 0.81
Hydrochloric Acid SCHEMBL7259157 0.79 ADRA1D (0.90) ADRA1D
SCHEMBL9636867 0.79 DRD2 (0.49)
SCHEMBL9757403 0.78 DRD2 (0.55)
SCHEMBL9636836 0.78
SCHEMBL7051875 0.78 DRD2 (0.56)
SCHEMBL9757388 0.77 HTR7 (0.66)
SCHEMBL9757518 0.77 CYP2D6 (0.62) ADRA1D
SCHEMBL9757367 0.76 DRD2 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5036075-A Serotonin antagonists RHONE-POULENC SANTE (FR) 1991-07-30 US disclosed
US-5021420-A Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders RHONE-POULENC SANTE (FR) 1991-06-04 US disclosed