Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.48 |
| ▸ | HTR1A | P08908 | 11/20 | 0.47 |
| ▸ | DRD2 | P14416 | 11/20 | 0.47 |
| ▸ | HTR2A | P28223 | 11/20 | 0.47 |
| ▸ | HTR6 | P50406 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720971 | 0.73 | HPGD (0.70) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9720957 | 0.70 | ALDH1A1 (0.67) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757358 | 0.70 | HTR7 (0.41) | HTR7HTR1ADRD2HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL9757172 | 0.69 | HTR7 (0.40) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757270 | 0.69 | HTR7 (0.51) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL7131251 | 0.68 | ALDH1A1 (0.71) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9290382 | 0.68 | HEXA (0.64) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9868832 | 0.68 | SIGMAR1 (0.39) | DRD2HTR2A | |
| SCHEMBL9720954 | 0.68 | MAPT (0.67) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL24991893 | 0.67 | HPGD (0.60) | HTR7HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |