SCHEMBL9757659

SCHEMBL9757659

Cc1cc(O)ccc1C(C)(C)CC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.52
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
MIF P14174 1/20 0.39
TYR P14679 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ESR1 P03372 7/20 0.36
ESR2 Q92731 7/20 0.36
CYP3A4 P08684 3/20 0.35
CHRM1 P11229 1/20 0.35
MAOA P21397 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13637095 0.84 ALOX15 (0.42) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL4403912 0.82 ESR2 (0.42) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL70826 0.82 SHBG (0.53) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL3218258 0.81 ALOX15 (0.40) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL31553273 0.79 ESR1 (0.42) ALOX15ALDH1A1NR1I2LMNACYP2C9
SCHEMBL18704832 0.79 ESR1 (0.42) ALOX15ALDH1A1NR1I2LMNACYP2C9
SCHEMBL9757664 0.79 CNR2 (0.46) ALOX15TYRHTTESR1ESR2
SCHEMBL29457550 0.78 ALDH1A1 (0.61) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL3441328 0.78 ALDH1A1 (0.61) SHBGALOX15ALDH1A1NR1I2LMNA
SCHEMBL28823864 0.78 ALOX15 (0.34) SHBGALOX15ALDH1A1NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024214743-A1 DIHYDROXYBIPHENYL COMPOUND, BISPHOSPHITE COMPOUND, CATALYST, CATALYST COMPOSITION, METHOD FOR PRODUCING ALDEHYDE, AND METHOD FOR PRODUCING ALCOHOL 三菱ケミカル株式会社 2024-10-17 WO disclosed
US-5049685-A Nuclear substituted salicylic acids and their salts SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1991-09-17 US disclosed