Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759092 | 0.93 | TP53 (0.34) | MAPK1RECQLALDH1A1POLBLMNA | |
| SCHEMBL9757776 | 0.91 | TLR4 (0.32) | MAPK1TLR4 | |
| SCHEMBL9757717 | 0.90 | TLR4 (0.32) | MAPK1ALDH1A1TLR4 | |
| SCHEMBL9758782 | 0.89 | NAAA (0.32) | MAPK1TLR4GAASMN1; SMN2 | |
| SCHEMBL9758906 | 0.88 | TLR4 (0.36) | ALDH1A1LMNAMAPTTLR4KMT2A | |
| SCHEMBL9758283 | 0.88 | NAAA (0.33) | MAPK1GAASMN1; SMN2 | |
| SCHEMBL9758693 | 0.84 | NAAA (0.36) | MAPTPKMMEN1KMT2A | |
| SCHEMBL9759646 | 0.84 | PKM (0.33) | MAPK1POLBLMNAMAPTPKM | |
| SCHEMBL9758624 | 0.84 | NAAA (0.34) | MAPK1ALDH1A1LMNAMAPTPKM | |
| SCHEMBL9759080 | 0.83 | NAAA (0.37) | MAPK1PKMMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |