Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757754 | 0.93 | MAPK1 (0.36) | MAPK1PKMLMNAPOLBMAPT | |
| SCHEMBL9758624 | 0.92 | NAAA (0.34) | TP53MAPK1PKMLMNAMAPT | |
| SCHEMBL9758693 | 0.92 | NAAA (0.36) | TP53PKMMAPTKMT2AMEN1 | |
| SCHEMBL9759646 | 0.92 | PKM (0.33) | TP53MAPK1PKMLMNAPOLB | |
| SCHEMBL9759080 | 0.91 | NAAA (0.37) | TP53MAPK1PKMKMT2AMEN1 | |
| SCHEMBL9757929 | 0.89 | CYP4F2 (0.36) | TP53MAPK1PKMLMNAPOLB | |
| SCHEMBL9758782 | 0.87 | NAAA (0.32) | MAPK1HTT | |
| SCHEMBL9758283 | 0.86 | NAAA (0.33) | MAPK1HTT | |
| SCHEMBL9757717 | 0.85 | TLR4 (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL9757776 | 0.84 | TLR4 (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |