SCHEMBL9757776

SCHEMBL9757776

CCCOC(=O)C1(CC[C@H]2CC[C@H](CCC)CC2)CCC(C2CCC(C)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757717 0.94 TLR4 (0.32) TLR4MAPK1
SCHEMBL9758782 0.93 NAAA (0.32) TLR4MAPK1
SCHEMBL9759646 0.93 PKM (0.33) MAPK1
SCHEMBL9758283 0.92 NAAA (0.33) MAPK1
SCHEMBL9757754 0.91 MAPK1 (0.36) TLR4MAPK1
SCHEMBL9758624 0.88 NAAA (0.34) MAPK1
SCHEMBL9758693 0.88 NAAA (0.36)
SCHEMBL9758906 0.87 TLR4 (0.36) TLR4
SCHEMBL9759080 0.87 NAAA (0.37) MAPK1
SCHEMBL9759092 0.84 TP53 (0.34) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985583-A Liquid Crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-15 US disclosed