SCHEMBL9758218

SCHEMBL9758218

COc1cc(C=CC(=O)OCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C)cc(OC)c1OC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 12/20 0.53
ABCG2 Q9UNQ0 12/20 0.53
ABCC1 P33527 11/20 0.53
ALOX5 P09917 2/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
MET P08581 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9758206 1.00 ABCB1 (0.53) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL16240912 0.84 KDM4E (0.50) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL16240911 0.84 KDM4E (0.50) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL6698837 0.83 ALDH1A1 (0.44) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL20335193 0.83 ALDH1A1 (0.44) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL17947814 0.82 KDM4E (0.49) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL20335167 0.82 KDM4E (0.49) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL17459720 0.79 ALOX5 (0.67) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL17459718 0.79 ALOX5 (0.67) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL9119106 0.77 ABCB1 (0.56) ABCB1ABCG2ABCC1ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3204887-A None JP disclosed
US-20240139085-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC PREPARATION, AND METHOD FOR PRODUCING SURFACE-MODIFIED ZINC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2024-05-02 US disclosed
EP-4296232-A1 SURFACE-MODIFIED ZINC OXIDE PAPRTICLES, DISPERSION LIQUID, COSMETIC PREPARATION, AND METHOD FOR PRODUCING SURFACE-MODIFIED ZINC OXIDE PARTICLES Sumitomo Osaka Cement Co., Ltd. (JP) 2023-12-27 EP disclosed
EP-4253323-A1 ZINC OXIDE POWDER, DISPERSION LIQUID, COATING MATERIAL, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2023-10-04 EP disclosed
EP-4253322-A1 ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2023-10-04 EP disclosed
US-20230263708-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION SOLUTION, AND COSMETIC SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2023-08-24 US disclosed
US-20230218488-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, LIQUID DISPERSION, AND COSMETIC SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2023-07-13 US disclosed
US-20230136530-A1 SURFACE-TREATED METAL OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC AND METHOD FOR PRODUCING SURFACE-TREATED METAL OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2023-05-04 US disclosed
EP-4144695-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION SOLUTION, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2023-03-08 EP disclosed
EP-4144696-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, LIQUID DISPERSION, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2023-03-08 EP disclosed
WO-2021066098-A1 W/O/W EMULSION COMPOSITION 株式会社 資生堂 2021-04-08 WO disclosed
WO-2020067406-A1 SURFACE-TREATED METAL OXIDE PARTICLES, LIQUID DISPERSION, COMPOSITION, COSMETIC, AND METHOD FOR PRODUCING SURFACE-TREATED METAL OXIDE PARTICLES 住友大阪セメント株式会社 2020-04-02 WO disclosed
WO-2020067417-A1 SURFACE-TREATED METAL OXIDE PARTICLES, LIQUID DISPERSION, COSMETIC, AND METHOD FOR PRODUCING SURFACE-TREATED METAL OXIDE PARTICLES 住友大阪セメント株式会社 2020-04-02 WO disclosed
EP-3342755-B1 ZINC OXIDE POWDER SUMITOMO OSAKA CEMENT CO LTD (JP) 2020-02-12 EP disclosed
US-20180256461-A1 ZINC OXIDE POWDER, DISPERSION, COMPOSITION, AND COSMETIC SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2018-09-13 US disclosed
EP-3342755-A1 ZINC OXIDE POWDER, DISPERSION, COMPOSITION, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2018-07-04 EP disclosed
EP-3252011-A1 ZINC OXIDE POWDER, DISPERSION, PAINT, COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2017-12-06 EP disclosed
US-20160221835-A1 ZINC OXIDE POWDER, DISPERSION, PAINT, AND COSMETIC MATERIAL SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2016-08-04 US disclosed
US-9403691-B1 Zinc oxide powder, dispersion, paint, and cosmetic material SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2016-08-02 US disclosed
JP-H03204887-A PRODUCTION OF SILICONE BASED CONNAMIC ACID DERIVATIVE SHISEIDO CO LTD 1991-09-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136530-A1 SURFACE-TREATED METAL OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC AND METHOD FOR PRODUCING SURFACE-TREATED METAL OXIDE PARTICLES CUTA, CD63, DSG1 ABCB1 4130/4885ABCG2 4101/4885ABCC1 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.