Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759315 | 0.93 | HTR1A (0.48) | HTR1A | |
| SCHEMBL9759922 | 0.86 | — | — | |
| SCHEMBL9527844 | 0.81 | HTR1A (0.55) | HTR1A | |
| SCHEMBL10661175 | 0.80 | HTR1A (0.56) | HTR1A | |
| SCHEMBL9526311 | 0.78 | HTR1A (0.58) | HTR1A | |
| SCHEMBL9527472 | 0.78 | HTR1A (0.55) | HTR1A | |
| SCHEMBL10556971 | 0.78 | HTR1A (0.55) | HTR1A | |
| SCHEMBL9759407 | 0.77 | DRD2 (0.60) | HTR1A | |
| SCHEMBL11005707 | 0.76 | HTR1A (0.56) | HTR1A | |
| SCHEMBL9822860 | 0.76 | HTR1A (0.58) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053508-A | Anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-10-01 | — | — | US | claimed |
| US-5053508-A | Anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-10-01 | — | — | US | disclosed |