Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9759845 | 0.99 | MAPT (0.55) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| SCHEMBL9760548 | 0.94 | MAPT (0.63) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| SCHEMBL9725384 | 0.87 | ALDH1A1 (0.56) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| SCHEMBL4980649 | 0.84 | SIRT5 (0.54) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| SCHEMBL762553 | 0.84 | SMN1; SMN2 (0.60) | MAPTLMNASMN1; SMN2TDP1ALPG | |
| SCHEMBL2013684 | 0.82 | SMN1; SMN2 (0.60) | MAPTLMNASMN1; SMN2TDP1ALPG | |
| SCHEMBL4981533 | 0.82 | SIRT5 (0.55) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL9760520 | 0.82 | SMN1; SMN2 (0.55) | MAPTAPPLMNASMN1; SMN2TDP1 | |
| SCHEMBL17749591 | 0.82 | MAPT (0.61) | MAPTLMNASMN1; SMN2TDP1ALPG | |
| SCHEMBL10580319 | 0.81 | MAPT (0.58) | MAPTLMNASMN1; SMN2TDP1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026401-A | Hair dyes | L'OREAL (FR) | 1991-06-25 | — | — | US | disclosed |