Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759928 | 1.00 | LMNA (0.40) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9331947 | 0.88 | LMNA (0.41) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9331955 | 0.88 | LMNA (0.41) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9759405 | 0.85 | CHRM2 (0.48) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9759408 | 0.85 | CHRM2 (0.48) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9331579 | 0.83 | USP2 (0.40) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9758879 | 0.83 | HTR1A (0.39) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9331883 | 0.83 | USP2 (0.40) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9758828 | 0.83 | CHRM2 (0.41) | LMNANOX1MAPTMAPK1TDP1 | |
| SCHEMBL9758824 | 0.83 | CHRM2 (0.41) | LMNANOX1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |