Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009144 | 0.79 | NPSR1 (0.77) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL975998 | 0.77 | NPSR1 (0.79) | NPSR1ALDH1A1MAPTGLAHTT | |
| SCHEMBL4408532 | 0.77 | NPSR1 (0.74) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL30408092 | 0.76 | NPSR1 (0.78) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL9283221 | 0.76 | NPSR1 (0.72) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL4410680 | 0.73 | NPSR1 (0.68) | NPSR1ALDH1A1MAPTHTTPOLB | |
| Hexane SCHEMBL8305527 | 0.72 | NPSR1 (0.66) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL842749 | 0.71 | ALDH1A1 (0.58) | NPSR1ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL13681117 | 0.71 | NPSR1 (0.64) | NPSR1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL30409337 | 0.70 | NPSR1 (0.59) | NPSR1ALDH1A1MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872146-B2 | Process for the preparation of a carboxamide derivative | BAYER CROPSCIENCE AG (DE) | 2011-01-18 | — | — | US | disclosed |
| EP-1881963-B1 | PROCESS FOR THE PREPARATION OF A CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-20090062552-A1 | PROCESS FOR THE PREPARATION OF A CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2009-03-05 | — | — | US | disclosed |
| EP-1881963-A1 | PROCESS FOR THE PREPARATION OF A CARBOXAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120031-A1 | PROCESS FOR THE PREPARATION OF A CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2006-11-16 | — | — | WO | disclosed |
| EP-1721899-A1 | Process for the preparation of a carboxamide derivative | Bayer CropScience S.A. (FR) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062552-A1 | PROCESS FOR THE PREPARATION OF A CARBOXAMIDE DERIVATIVE | CPS1, SDHA, CS | NPSR1 1789/4885ALDH1A1 284/4885MAPT 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.