Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866451 | 0.80 | FNTA (0.48) | — | |
| SCHEMBL10582405 | 0.79 | GAA (0.40) | — | |
| SCHEMBL9760033 | 0.78 | SIRT6 (0.39) | CA12CA9 | |
| SCHEMBL8916747 | 0.77 | TBXAS1 (0.45) | CA12CA9 | |
| SCHEMBL9190610 | 0.76 | HTR5A (0.38) | — | |
| SCHEMBL7453705 | 0.74 | HTR5A (0.40) | — | |
| SCHEMBL669278 | 0.74 | KDM4E (0.46) | — | |
| SCHEMBL9285801 | 0.73 | IP6K1 (0.51) | CA12CA9 | |
| SCHEMBL9663508 | 0.72 | IDO1 (0.37) | — | |
| SCHEMBL9663761 | 0.72 | CYP11B1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037829-A | Antitumor Activity; Androgen, Estrogen Inhibitors; Suppress The Plasma Elimination Of Retinoids | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-06 | — | — | US | claimed |
| US-5037829-A | Antitumor Activity; Androgen, Estrogen Inhibitors; Suppress The Plasma Elimination Of Retinoids | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-06 | — | — | US | disclosed |