Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419860 | 0.93 | ALDH1A1 (0.58) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL631998 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL27883 | 0.80 | CA12 (0.65) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL699457 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL699458 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL4881152 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL13790336 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL14950253 | 0.80 | RELA (0.81) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| Anethole SCHEMBL57011 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4LMNATP53 | |
| Anethole SCHEMBL48599 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052356-A1 | INHIBITORS OF THE CERAMIDE METABOLIC PATHWAY FOR OVERCOMING IMMUNOTHERAPY RESISTANCE IN CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-03-14 | — | — | WO | claimed |
| EP-4273135-A1 | PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-11-08 | — | — | EP | claimed |
| CN-116710440-A | Plasmin inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116143631-A | Pd/SnO 2 Method for preparing nitrogen-containing aromatic compound by catalyzing lignin | 中国科学院大连化学物理研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-116143638-A | Method for preparing nitrogen-containing aromatic compound by catalyzing lignin through Fe-terpyridine | 中国科学院大连化学物理研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-116120271-A | Genipin derivative and preparation method and application thereof | 广东工业大学 | 2023-05-16 | — | — | CN | claimed |
| EP-3424913-B1 | 2,3-EPOXY SUCCINYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USES THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2023-04-05 | — | — | EP | claimed |
| CN-115353506-A | 3-substituted phenanthridine compound, preparation method and application thereof, and pharmaceutical composition | 苏州施安鼎泰生物医药技术有限公司 | 2022-11-18 | — | — | CN | claimed |
| WO-2022117389-A1 | METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER | BASF SE (DE) | 2022-06-09 | — | — | WO | claimed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | claimed |
| EP-0543780-A2 | Novel aminoalkanephosphinic acids and their salts | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | claimed |
| EP-0515514-A4 | 2-ARALKOXY AND 2-ALKOXY ADENOSINE DERIVATIVES AS CORONARY VASODILATORS AND ANTIHYPERTENSIVE AGENTS | — | 1993-01-13 | — | — | EP | claimed |
| EP-0515514-A1 | 2-ARALKOXY AND 2-ALKOXY ADENOSINE DERIVATIVES AS CORONARY VASODILATORS AND ANTIHYPERTENSIVE AGENTS | WHITBY RESEARCH, Inc. (US) | 1992-12-02 | — | — | EP | claimed |
| US-5140015-A | Racemic mixture for inducing an adenosine response in humans and animals | WHITBY RESEARCH, INC. (US) | 1992-08-18 | — | — | US | claimed |
| WO-1991013082-A1 | 2-ARALKOXY AND 2-ALKOXY ADENOSINE DERIVATIVES AS CORONARY VASODILATORS AND ANTIHYPERTENSIVE AGENTS | WHITBY RESEARCH, INC. (US) | 1991-09-05 | — | — | WO | claimed |
| EP-0343307-A1 | 4-Piperidinealkanamine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1989-11-29 | — | — | EP | claimed |
| EP-0161841-B1 | 2-(N-SUBSTITUTEGUANIDINO)-4-HETERO-ARYLTHIAZOLE ANTIULCER AGENTS | PFIZER INC. (US) | 1989-07-19 | — | — | EP | claimed |
| US-4566996-A | Process for preparing azetidinone derivatives | Otsuke Kagaku Yakuhin Kabushiki Kaisha (JP) | 1986-01-28 | — | — | US | claimed |
| US-4560690-A | ANTISECRETORY AGENTS, HISTAMINE H2-ANTAGONISTS | PFIZER INC. (US) | 1985-12-24 | — | — | US | claimed |
| EP-0161841-A1 | 2-(N-substituteguanidino)-4-hetero-arylthiazole antiulcer agents | PFIZER INC. (US) | 1985-11-21 | — | — | EP | claimed |