Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792974 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL9761046 | 0.83 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL10774291 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL9760348 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL9761030 | 0.79 | HTR6 (0.46) | KDM4EHSD17B10TSHRHTR6 | |
| SCHEMBL10774163 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL9760954 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDLMNAHTR6 | |
| SCHEMBL9830824 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL10774016 | 0.75 | HTR6 (0.41) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL10775013 | 0.73 | MAPT (0.46) | KDM4EALDH1A1HSD17B10TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | claimed |
| US-5021591-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |