Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759516 | 0.86 | ALDH1A1 (0.47) | ALDH1A1ADRA2AMAPTADRA2BADRA2C | |
| SCHEMBL9759503 | 0.86 | ALDH1A1 (0.46) | ALDH1A1ADRA2AMAPTADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9759454 | 0.84 | ADRA2A (0.52) | ALDH1A1ADRA2AMAPTADRA2BADRA2C | |
| Tioperidone SCHEMBL29385311 | 0.82 | ADRA2A (0.58) | ALDH1A1ADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL9759789 | 0.81 | ADRA2A (0.57) | ALDH1A1ADRA2AMAPTADRA2BADRA2C | |
| Tioperidone SCHEMBL122658 | 0.81 | ADRA2A (0.57) | ALDH1A1ADRA2AADRA2BADRA2CSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9760154 | 0.80 | ADRA2A (0.56) | ALDH1A1ADRA2AMAPTADRA2BADRA2C | |
| SCHEMBL9447015 | 0.77 | ADRA2A (0.59) | ALDH1A1ADRA2AADRA2BADRA2CHTR1A | |
| Hydrochloric Acid SCHEMBL9760181 | 0.76 | ADRA2A (0.56) | ALDH1A1ADRA2AADRA2BADRA2CSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9760407 | 0.75 | LMNA (0.49) | ALDH1A1ADRA2AMAPTADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012006-A2 | TUMOR CELL SENSITIZATION METHOD | WARNER-LAMBERT COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |