Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119284 | 0.84 | MEN1 (0.50) | NPC1RAB9AALDH1A1CYP3A4TRIM24 | |
| SCHEMBL9560109 | 0.81 | MAOB (0.57) | NPC1RAB9AALDH1A1ARPGR | |
| SCHEMBL910364 | 0.80 | NPC1 (0.53) | NPC1RAB9AALDH1A1CYP3A4TRIM24 | |
| SCHEMBL4252680 | 0.79 | GLA (0.49) | NPC1RAB9AALDH1A1HPGDMAPK1 | |
| SCHEMBL12116989 | 0.79 | MAOB (0.43) | NPC1RAB9AALDH1A1ARMAPT | |
| SCHEMBL15201858 | 0.78 | AR (0.47) | NPC1RAB9AALDH1A1MAPK1AR | |
| SCHEMBL509379 | 0.78 | AR (0.50) | NPC1RAB9AALDH1A1MAPK1AR | |
| SCHEMBL30730992 | 0.78 | ALDH1A1 (0.63) | NPC1RAB9AALDH1A1ARPGR | |
| SCHEMBL1762094 | 0.78 | ALDH1A1 (0.63) | NPC1RAB9AALDH1A1ARPGR | |
| SCHEMBL1608900 | 0.78 | AR (0.69) | ALDH1A1CYP3A4ARPGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504622-A | Preparation method of 2,4, 6-tri (2-hydroxy-4-n-butoxyphenyl) -1,3, 5-triazine | 安徽英特美科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | claimed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | claimed |
| CN-101402610-A | Synthesis method of 4-(3-chlorine-4-fluorobenzene amino)-7-methoxy-6-[3-(4-morpholinyl)-propoxy] quinoline | ZHEJIANG EXCEL PHARMACEUTICAL (CN) | 2009-04-08 | — | — | CN | claimed |
| CN-119504622-A | Preparation method of 2,4, 6-tri (2-hydroxy-4-n-butoxyphenyl) -1,3, 5-triazine | 安徽英特美科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119504622-A | Preparation method of 2,4, 6-tri (2-hydroxy-4-n-butoxyphenyl) -1,3, 5-triazine | 安徽英特美科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20230365730-A1 | HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF | KANEKA CORPORATION (JP) | 2023-11-16 | — | — | US | disclosed |
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | disclosed |
| CN-115040497-A | Application of paeonol derivative in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-09-13 | — | — | CN | disclosed |
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022069948-A1 | HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF | KANEKA CORPORATION (JP) | 2022-04-07 | — | — | WO | disclosed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | disclosed |
| WO-1999024433-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |
| EP-0731099-A1 | N-(3-benzofuranyl)urea-derivatives | BAYER AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5198439-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5130318-A | Hypotensive agents and for treatment of congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-14 | — | — | US | disclosed |
| EP-0257583-B1 | PROCESS FOR ORTHO-CYANATION OF PHENOLS OR PHENYLAMINES | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |
| US-4774331-A | THIOCYANATION IN PRESENCE OF BORON TRIFLUORIDE | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0257583-A1 | Process for ortho-cyanation of phenols or phenylamines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365730-A1 | HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF | KDM5C, DHX15, KDM5A | NPC1 4840/4885RAB9A 4475/4885ALDH1A1 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.