Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760048 | 0.83 | HCAR3 (0.47) | ALDH1A1KDM4EHCAR3ALDH3A1SMN1; SMN2 | |
| SCHEMBL182012 | 0.77 | HCAR3 (0.49) | ALDH1A1KDM4EHCAR3ALDH3A1SMN1; SMN2 | |
| SCHEMBL5821559 | 0.74 | HCAR3 (0.48) | ALDH1A1KDM4EHCAR3POLBALDH3A1 | |
| SCHEMBL688642 | 0.74 | HCAR3 (0.51) | ALDH1A1KDM4EHCAR3POLBALDH3A1 | |
| SCHEMBL15049708 | 0.73 | HCAR3 (0.63) | ALDH1A1KDM4EHCAR3POLBSMN1; SMN2 | |
| SCHEMBL18342758 | 0.70 | HCAR3 (0.56) | ALDH1A1HCAR3ALDH3A1SMN1; SMN2MAPT | |
| SCHEMBL8448326 | 0.69 | HCAR3 (0.55) | ALDH1A1KDM4EHCAR3ALDH3A1SMN1; SMN2 | |
| SCHEMBL8935979 | 0.69 | HCAR3 (0.55) | ALDH1A1KDM4EHCAR3POLBALDH3A1 | |
| SCHEMBL9769611 | 0.69 | HCAR3 (0.53) | ALDH1A1KDM4EHCAR3POLBALDH3A1 | |
| SCHEMBL9281293 | 0.68 | PDK1 (0.55) | ALDH1A1POLBTDP1HTTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026401-A | Hair dyes | L'OREAL (FR) | 1991-06-25 | — | — | US | disclosed |