SCHEMBL182012

SCHEMBL182012

CCN(O)c1ccc(O)cc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 4/20 0.49
ALDH3A1 P30838 2/20 0.47
ALDH1A1 P00352 5/20 0.41
HTT P42858 3/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BACE1 P56817 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
TP53 P04637 1/20 0.39
AR P10275 1/20 0.38
EGFR P00533 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688642 0.88 HCAR3 (0.51) HCAR3ALDH3A1ALDH1A1HTTMAPT
SCHEMBL7041286 0.84 TSHR (0.53) HCAR3ALDH3A1ALDH1A1HTTMAPT
SCHEMBL1886680 0.83 ALDH1A1 (0.51) HCAR3ALDH3A1ALDH1A1HTTMAPT
SCHEMBL9760048 0.81 HCAR3 (0.47) HCAR3ALDH3A1ALDH1A1HTTMAPT
SCHEMBL11271182 0.80 POLB (0.52) HCAR3ALDH3A1ALDH1A1MAPTMEN1
SCHEMBL15534710 0.80 ALDH1A1 (0.49) HCAR3ALDH3A1ALDH1A1HTTKMT2A
SCHEMBL15049708 0.80 HCAR3 (0.63) HCAR3ALDH1A1HTTMAPTKMT2A
SCHEMBL1455684 0.79 MAPK1 (0.49) HCAR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL3655437 0.78 ALDH1A1 (0.46) HCAR3ALDH1A1HTTMAPTMEN1
SCHEMBL25378565 0.77 ALDH1A1 (0.55) HCAR3ALDH3A1ALDH1A1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 953 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115980205-B Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product 江苏省食品药品监督检验研究院 2025-04-22 CN claimed
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-24 US claimed
US-12036299-B2 Compositions containing direct dyes for imparting color and tone to the hair L'OREAL (FR) 2024-07-16 US claimed
EP-4362902-A1 COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR L'OREAL (FR) 2024-05-08 EP claimed
CN-115980205-A Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product 江苏省食品药品监督检验研究院 2023-04-18 CN claimed
WO-2023017035-A1 HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS WELLA GERMANY GMBH (DE) 2023-02-16 WO claimed
US-20230025989-A1 COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR L'OREAL (FR) 2023-01-26 US claimed
WO-2023278726-A1 COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR L'OREAL (FR) 2023-01-05 WO claimed
CN-114246807-A Acidic hair dye composition 朋友株式会社 2022-03-29 CN claimed
CN-112955112-A Two-component system for artificial hair coloring 汉高股份有限及两合公司 2021-06-11 CN claimed
US-20100189670-A1 METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 US claimed
US-7736633-B2 Method for enhancing effects of colorants and conditioners E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-15 US claimed
WO-2010022055-A2 INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS AMGEN INC. (US) 2010-02-25 WO claimed
US-20090074694-A1 DYED-HAIR-BINDING PEPTIDES AND PEPTIDE-BASED HAIR REAGENTS FOR PERSONAL CARE AFFINERGY, LLC. 2009-03-19 US claimed
US-20080189876-A1 Multistep hair color revitalizing kit and associated methods PROCTER & GAMBLE COMPANY, THE 2008-08-14 US claimed
EP-1928397-A1 METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS E.I.Du pont de nemours and company (US) 2008-06-11 EP claimed
US-20070251028-A1 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent L'OREAL S.A. (FR) 2007-11-01 US claimed
EP-1844816-A2 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent L'Oréal (FR) 2007-10-17 EP claimed
WO-2007038733-A1 METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-05 WO claimed
US-20070067924-A1 Method for enhancing effects of colorants and conditioners E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025989-A1 COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR PHOSPHO1, TYR, AADAT HCAR3 1205/4885ALDH3A1 1570/4885ALDH1A1 1243/4885
US-20070251028-A1 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent KRT18, DSG1, IK HCAR3 2420/4885ALDH3A1 41/4885ALDH1A1 18/4885
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents TYR, OGG1, UNG HCAR3 585/4885ALDH3A1 122/4885ALDH1A1 6/4885
US-12036299-B2 Compositions containing direct dyes for imparting color and tone to the hair PHOSPHO1, TYR, AADAT HCAR3 1205/4885ALDH3A1 1570/4885ALDH1A1 1243/4885
US-20090074694-A1 DYED-HAIR-BINDING PEPTIDES AND PEPTIDE-BASED HAIR REAGENTS FOR PERSONAL CARE TAP1, RBP1, CUTA HCAR3 1045/4885ALDH3A1 2405/4885ALDH1A1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.