SCHEMBL9760860

SCHEMBL9760860

O=C1CCON1Cc1ccnnc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.39
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
KCNQ2 O43526 1/20 0.35
HSD17B10 Q99714 1/20 0.34
IKZF2 Q9UKS7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9762141 0.83 KDM4E (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9762485 0.77 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL44669 0.76 L3MBTL1 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7847449 0.76 L3MBTL1 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL18763113 0.73 ALDH1A1 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9762493 0.73 BRD4 (0.40) LOXL2KCNQ2HSD17B10
SCHEMBL9762399 0.72 BRD4 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6950745 0.69 L3MBTL1 (0.53) LOXL2
SCHEMBL9761755 0.69 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9762460 0.69 RIPK3 (0.37) LOXL2CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066665-A Cognition activators; alzheimer*s disease WARNER-LAMBERT CO. (US) 1991-11-19 US disclosed