Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 5/20 | 0.43 |
| ▸ | GSK3B | P49841 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44669 | 1.00 | L3MBTL1 (0.45) | L3MBTL1F2PLGELANECTSG | |
| SCHEMBL9762141 | 0.82 | KDM4E (0.39) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18763113 | 0.82 | ALDH1A1 (0.44) | POLBALDH1A1THRBCHRM2CHRM4 | |
| SCHEMBL27248243 | 0.80 | SMN1; SMN2 (0.46) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11731516 | 0.78 | ALDH1A1 (0.44) | F2PLGELANECTSGCMA1 | |
| SCHEMBL9760860 | 0.76 | LOXL2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9762485 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29403464 | 0.73 | KMT2A (0.47) | L3MBTL1POLBALDH1A1THRBMEN1 | |
| SCHEMBL29402636 | 0.73 | TP53 (0.42) | L3MBTL1POLBGAAALDH1A1MEN1 | |
| SCHEMBL10585672 | 0.71 | TACR1 (0.37) | L3MBTL1F2PLGELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069125-A2 | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments | AVENTIS PHARMACEUTICALS INC. (US) | 2001-01-17 | — | — | EP | claimed |