SCHEMBL44669

SCHEMBL44669

O=C1CCON1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
CMA1 P23946 1/20 0.44
CTRC Q99895 1/20 0.44
POLB P06746 1/20 0.44
GSK3A P49840 5/20 0.43
GSK3B P49841 5/20 0.43
GAA P10253 2/20 0.42
MGLL Q99685 1/20 0.41
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.40
CHRM2 P08172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7847449 1.00 L3MBTL1 (0.45) L3MBTL1F2PLGELANECTSG
SCHEMBL9762141 0.82 KDM4E (0.39) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL18763113 0.82 ALDH1A1 (0.44) POLBALDH1A1THRBCHRM2CHRM4
SCHEMBL27248243 0.80 SMN1; SMN2 (0.46) KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL11731516 0.78 ALDH1A1 (0.44) F2PLGELANECTSGCMA1
SCHEMBL9760860 0.76 LOXL2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9762485 0.75 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29403464 0.73 KMT2A (0.47) L3MBTL1POLBALDH1A1THRBMEN1
SCHEMBL29402636 0.73 TP53 (0.42) L3MBTL1POLBGAAALDH1A1MEN1
SCHEMBL10585672 0.71 TACR1 (0.37) L3MBTL1F2PLGELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines BASF SE (DE) 2019-07-02 US claimed
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2017-12-28 US claimed
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2016-02-11 US claimed
WO-2025229557-A1 ISOXAZOLIDINONE HERBICIDE MICROCAPSULES, FORMULATIONS AND METHODS OF USE AND PREPARATION THEREOF ADAMA AGAN LTD. (IL) 2025-11-06 WO disclosed
CN-119233756-A Method and composition for herbicidal mixtures with synergistic action 专业农场集团有限公司 2024-12-31 CN disclosed
CN-114885952-B Novel herbicidal compounds 马罗内生物创新公司 2024-07-23 CN disclosed
US-20240023554-A1 MICROPARTICLE COMPOSITIONS COMPRISING TRIFLUDIMOXAZIN BASF SE (DE) 2024-01-25 US disclosed
WO-2023212300-A1 METHOD AND COMPOSITION OF SYNERGISTIC HERBICIDAL MIXTURES PRO FARM GROUP, INC. (US) 2023-11-02 WO disclosed
EP-4258872-A1 MICROPARTICLE COMPOSITIONS COMPRISING TRIFLUDIMOXAZIN BASF SE (DE) 2023-10-18 EP disclosed
EP-3979798-B1 MICROPARTICLE COMPOSITIONS COMPRISING SAFLUFENACIL BASF AGRO BV (NL) 2023-04-26 EP disclosed
CN-114885952-A Novel herbicidal compounds 马罗内生物创新公司 2022-08-12 CN disclosed
WO-1997002253-A1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
WO-1996028442-A1 3-ARYLURACILS AND INTERMEDIATES FOR THEIR PREPARATION BASF AKTIENGESELLSCHAFT (DE) 1996-09-19 WO disclosed
EP-0728753-A1 5-Tetrahydropyranone-cyclohexenone oxime ethers and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1996-08-28 EP disclosed
WO-1996024590-A1 NOVEL 3-(4-CYANOPHENYL)URACILS BASF AKTIENGESELLSCHAFT (DE) 1996-08-15 WO disclosed
WO-1996021645-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
WO-1996021646-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
WO-1996021647-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
US-4552585-A Herbicidal 2-(aminophenyl)methyl derivatives of 3-isoxazolidinones or 3-oxazinones FMC CORPORATION (US) 1985-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 L3MBTL1 3147/4885F2 2290/4885PLG 3658/4885
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 L3MBTL1 3147/4885F2 2290/4885PLG 3658/4885
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 L3MBTL1 3147/4885F2 2290/4885PLG 3658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.