Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816829 | 0.78 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1616607 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL1616609 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL19690939 | 0.75 | KDM4E (0.52) | KDM4ELMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19690946 | 0.75 | LMNA (0.52) | KDM4ELMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11769911 | 0.74 | KMT2A (0.54) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL12356700 | 0.73 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1ADORA2A | |
| SCHEMBL4816783 | 0.73 | MAPT (0.60) | ALDH1A1KDM4ELMNASMN1; SMN2ABCG2 | |
| SCHEMBL9760934 | 0.73 | RIPK1 (0.60) | ALDH1A1LMNASMN1; SMN2ABCG2KMT2A | |
| SCHEMBL9056686 | 0.71 | NPC1 (0.59) | KDM4ELMNASMN1; SMN2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |