Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066108 | 0.76 | LMNA (0.58) | RIPK1MAPTLMNAPOLBGAA | |
| SCHEMBL1473102 | 0.76 | LMNA (0.58) | RIPK1MAPTLMNAPOLBGAA | |
| SCHEMBL3857798 | 0.75 | SMN1; SMN2 (0.47) | RIPK1MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL4108967 | 0.75 | MEN1 (0.43) | RIPK1LMNAALDH1A1SMN1; SMN2HTR3E | |
| SCHEMBL3403294 | 0.75 | MEN1 (0.43) | RIPK1LMNAALDH1A1SMN1; SMN2HTR3E | |
| SCHEMBL2789608 | 0.75 | LMNA (0.59) | RIPK1MAPTLMNAPOLBGAA | |
| SCHEMBL9760892 | 0.73 | ALDH1A1 (0.51) | RIPK1LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3401635 | 0.73 | HDAC6 (0.37) | RIPK1MAPTALDH1A1ABCG2HTR3E | |
| SCHEMBL3413339 | 0.72 | HTR1A (0.40) | RIPK1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7097532 | 0.72 | HTR1A (0.50) | RIPK1MAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |