SCHEMBL6527669

SCHEMBL6527669

O=C(O)c1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.69
KDM4E B2RXH2 7/20 0.69
KMT2A Q03164 6/20 0.69
HPGD P15428 6/20 0.69
MEN1 O00255 5/20 0.69
MAPT P10636 4/20 0.69
HTT P42858 3/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
NPC1 O15118 1/20 0.69
RAB9A P51151 1/20 0.69
CYP3A4 P08684 4/20 0.66
LMNA P02545 3/20 0.66
MAPK1 P28482 3/20 0.66
ALOX15 P16050 2/20 0.66
TP53 P04637 2/20 0.66
CA12 O43570 1/20 0.66
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
ABCB1 P08183 1/20 0.66
CALM1 P0DP23 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429303 0.90 RET (0.63) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL5579331 0.88 KDM4E (0.57) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL311250 0.87 KDM4E (0.62) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL27784285 0.87 KMT2A (0.63) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL9873754 0.87 KDM4E (0.62) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL26031862 0.87 KMT2A (0.62) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL31723137 0.86 KDM4E (0.72) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL31723120 0.86 KMT2A (0.57) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL20918216 0.86 KMT2A (0.57) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL28429262 0.86 KDM4E (0.72) ALDH1A1KDM4EKMT2AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119936250-A Construction method of ginseng and motherwort blood-nourishing particle fingerprint and fingerprint thereof 陕西白鹿制药股份有限公司 2025-05-06 CN claimed
CN-115961380-B Homogeneous coating fiber material based on electrostatic-jet coaxial spinning and preparation method thereof 上海工程技术大学 2025-03-14 CN claimed
CN-114989123-B Flavone-3-carboxylic acid compound, bactericidal composition containing same and application thereof 长江大学 2024-05-31 CN claimed
CN-117529549-A Cell culture food products and related cells, compositions, methods and systems 布鲁纳卢公司 2024-02-06 CN claimed
CN-114989123-A Flavone-3-carboxylic acid compound, bactericidal composition containing compound and application 长江大学 2022-09-02 CN claimed
EP-0290915-B1 FLAVONE-3-CARBOXYLIC-ACID COMPOUNDS, AND PROCESS, INTERMEDIATES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Kali-Chemie Pharma GmbH (DE) 1993-07-14 EP claimed
EP-0237986-B1 FLAVONE CARBOXYLIC ACID DERIVATIVES Shudo, Koichi, Prof. Dr. (JP) 1991-10-02 EP claimed
US-5013852-A Antiinflammatory KALI-CHEMIE PHARMA GMBH (DE) 1991-05-07 US claimed
US-4886806-A ANTIINFLAMMATORY AGENTS KALI-CHEMIE PHARMA GMBH (DE) 1989-12-12 US claimed
US-4831052-A DIFFERENTIATION-INDUCING AGENT FOR CERTAIN MALIONANT CELLS SHIONOGI & CO., LTD. (JP) 1989-05-16 US claimed
EP-0237986-A2 Flavone carboxylic acid derivatives Shudo, Koichi, Prof. Dr. (JP) 1987-09-23 EP claimed
JP-6025211-A None JP disclosed
JP-61238783-A None JP disclosed
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP disclosed
EP-2421805-B2 USE OF A UV OR IR ACTIVE COMPONENT AS A MARKER OR IDENTIFIER IN A MINERAL WOOL INSULATION PRODUCT KNAUF INSULATION (BE) 2025-06-18 EP disclosed
EP-0290915-A2 Flavone-3-carboxylic-acid compounds, and process, intermediates for their preparation and medicines containing these compounds Kali-Chemie Pharma GmbH (DE) 1988-11-17 EP disclosed
EP-0237986-A2 Flavone carboxylic acid derivatives Shudo, Koichi, Prof. Dr. (JP) 1987-09-23 EP disclosed
EP-0237986-A2 Flavone carboxylic acid derivatives Shudo, Koichi, Prof. Dr. (JP) 1987-09-23 EP disclosed
EP-0237986-A2 Flavone carboxylic acid derivatives Shudo, Koichi, Prof. Dr. (JP) 1987-09-23 EP disclosed
JP-S61238783-A FLAVONE CARBOXAMIDE DERIVATIVE HOKURIKU SEIYAKU CO LTD 1986-10-24 JP disclosed