SCHEMBL11360558

SCHEMBL11360558

O=C(O)c1oc2ccccc2c(=O)c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
MAOA P21397 4/20 0.53
CYP3A4 P08684 3/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
PGAM1 P18669 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
TTR P02766 4/20 0.53
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
ALOX15 P16050 2/20 0.51
MAPK1 P28482 2/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520307 0.87 KMT2A (0.50) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL752884 0.82 KDM4E (0.65) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL9760981 0.81 CYP2C9 (0.66) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL7092243 0.81 MAOA (0.52) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL6045428 0.81 TTR (0.52) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL29587413 0.81 TTR (0.52) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL6527669 0.79 ALDH1A1 (0.69) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL3417705 0.79 CA1 (0.61) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL29591307 0.79 CA1 (0.61) KDM4EMAOACYP3A4MAPTALDH1A1
SCHEMBL15820937 0.79 TTR (0.50) KDM4EMAOACYP3A4MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462701-A Preparation and application of tetrapyridine copper oxalate metal complex 合肥工业大学 2025-02-18 CN disclosed
US-4307020-A REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
US-4285965-A FUNGICIDES AND INSECTICIDES FOR PLANTS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed
US-4189498-A FUNGICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed