Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | TGM1 | P22735 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450952 | 0.84 | GRIN2B (0.71) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL5364470 | 0.82 | TPSAB1 (0.62) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL9760056 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL13439706 | 0.81 | GRIN2B (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL6593704 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL13168269 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL460173 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL387354 | 0.79 | GPR119 (0.56) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7035676 | 0.79 | GRIN2B (0.58) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 | |
| SCHEMBL3554740 | 0.78 | SIGMAR1 (0.57) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057528-A | AMINO-PYRIDINE COMPOUNDS USEFUL AS ANTI-ARRHYTHMIC AGENTS | PFIZER INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4968704-A | PROLONG DURATION OF ACTION POTENTIAL IN CARDIAC MUSCLE AND CONDUCTING TISSUE | PFIZER INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0359389-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1990-03-21 | — | — | EP | disclosed |