Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760898 | 0.83 | SLC6A9 (0.42) | SLC6A9 | |
| SCHEMBL10382570 | 0.83 | SLC6A9 (0.44) | SLC6A9OPRM1OPRD1OPRK1HRH3 | |
| SCHEMBL9760636 | 0.81 | RAD52 (0.43) | SLC6A9 | |
| SCHEMBL10444904 | 0.80 | SLC6A9 (0.67) | SLC6A9NPSR1 | |
| SCHEMBL9762111 | 0.80 | SLC6A9 (0.46) | SLC6A9OPRM1OPRD1OPRK1NPSR1 | |
| SCHEMBL9536097 | 0.77 | SLC6A9 (0.45) | SLC6A9OPRM1OPRD1OPRK1HRH3 | |
| SCHEMBL9535360 | 0.77 | HRH1 (0.54) | SLC6A9OPRM1OPRD1OPRK1HRH3 | |
| SCHEMBL9535868 | 0.77 | SLC6A9 (0.44) | SLC6A9HRH1 | |
| SCHEMBL9536586 | 0.76 | SLC6A9 (0.41) | SLC6A9OPRM1OPRD1OPRK1HRH1 | |
| Hydrochloric Acid SCHEMBL10384124 | 0.76 | SLC6A9 (0.44) | SLC6A9HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |