SCHEMBL9761798

SCHEMBL9761798

C[SiH](C)c1ccc(Sc2ccc([SiH](C)C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DDAH1 O94760 1/20 0.36
NOS1 P29475 1/20 0.36
ALDH1A1 P00352 1/20 0.34
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
MLYCD O95822 1/20 0.31
SLC6A4 P31645 1/20 0.31
STS P08842 1/20 0.31
PTGIR P43119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148576 0.83
SCHEMBL2438805 0.83
SCHEMBL13473462 0.82 ALDH1A1 (0.42) NOS1ALDH1A1MAOASLC6A4
SCHEMBL2579397 0.73 ALDH1A1 (0.32) CYP3A4ALDH1A1
SCHEMBL476102 0.71 ACHE (0.53) TSHRLMNAALDH1A1
SCHEMBL20079476 0.69 MAOA (0.43) NR1H2CYP3A4TSHRMAPK1HPGD
SCHEMBL17656438 0.69 IDO1 (0.38)
SCHEMBL21485125 0.69
SCHEMBL13645585 0.69 TPMT (0.38)
SCHEMBL8339224 0.69 CYP2A6 (0.50) TSHRMAPK1NOS1ALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3215490-A None JP disclosed
US-12497511-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2025-12-16 US disclosed
US-12187854-B2 Crosslinkable organosiloxane compositions WACKER CHEMIE AG (DE) 2025-01-07 US disclosed
US-12110393-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2024-10-08 US disclosed
CN-112996841-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-12-27 CN disclosed
CN-111936582-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-06-17 CN disclosed
CN-111936556-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-05-03 CN disclosed
EP-3837317-B1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2022-04-20 EP disclosed
US-20210347952-A1 CROSSLINKABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-11-11 US disclosed
US-20210309856-A1 CROSSLINKABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-10-07 US disclosed
EP-3837317-A1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2021-06-23 EP disclosed
EP-3837304-A1 CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2021-06-23 EP disclosed
EP-3837305-A1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2021-06-23 EP disclosed
CN-112996841-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2021-06-18 CN disclosed
CN-111936582-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2020-11-13 CN disclosed
CN-111936556-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2020-11-13 CN disclosed
WO-2020035149-A1 CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2020-02-20 WO disclosed
WO-2020035152-A1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2020-02-20 WO disclosed
WO-2020035151-A1 CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2020-02-20 WO disclosed
JP-H03215490-A DIPHENYL SULFIDE COMPOUND, ITS PRODUCTION AND INTERMEDIATE FOR PRODUCTION THEREOF YUKI GOSEI KOGYO CO LTD 1991-09-20 JP disclosed