Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795119 | 0.85 | MCL1 (0.46) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL9762907 | 0.80 | KMT2A (0.52) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28285614 | 0.77 | RAPGEF4 (0.52) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL10795153 | 0.76 | NPC1 (0.46) | LMNAGAAPOLBALDH1A1MAPT | |
| SCHEMBL10794994 | 0.73 | HPGD (0.50) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10797278 | 0.71 | KCNQ2 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL1688411 | 0.70 | RAPGEF4 (0.49) | MEN1KMT2AGAAPOLBMAPT | |
| SCHEMBL19910569 | 0.70 | LMNA (0.62) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL9761992 | 0.70 | GAA (0.50) | LMNAKMT2AGAAPOLBALDH1A1 | |
| SCHEMBL11287941 | 0.69 | RAPGEF4 (0.55) | LMNAGAAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |