Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797278 | 0.80 | KCNQ2 (0.42) | NPC1RAB9AHPGD | |
| SCHEMBL27814106 | 0.77 | LMNA (0.45) | HPGDALDH1A1GAAMAPTLMNA | |
| SCHEMBL10800203 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL9761988 | 0.76 | LMNA (0.46) | ALDH1A1GAAKDM4EPOLBMAPT | |
| SCHEMBL1608004 | 0.75 | TDP1 (0.52) | HPGDALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL26385190 | 0.74 | NPC1 (0.48) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL2230553 | 0.74 | NPC1 (0.48) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL4750832 | 0.73 | MAPT (0.50) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL30461968 | 0.73 | MAPT (0.50) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL245209 | 0.73 | MAPT (0.50) | NPC1RAB9AHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |