Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761408 | 0.74 | KMT2A (0.41) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762128 | 0.73 | KMT2A (0.44) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9761232 | 0.71 | KMT2A (0.50) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762582 | 0.70 | PGK1 (0.40) | CYP1A2TDP1MAPTGAAATM | |
| SCHEMBL9762389 | 0.68 | KMT2A (0.43) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762197 | 0.68 | PGK1 (0.38) | RAB9AMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL9762323 | 0.68 | NPC1 (0.49) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9789043 | 0.64 | PGK1 (0.40) | KMT2AMEN1NPC1RAB9AADORA3 | |
| SCHEMBL9762328 | 0.64 | NPC1 (0.50) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762260 | 0.64 | ALDH1A1 (0.41) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |