Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435550 | 0.81 | LMNA (0.41) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9762197 | 0.78 | PGK1 (0.38) | PGK1MAPTALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL10887538 | 0.74 | MAPT (0.38) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL958749 | 0.71 | NOS1 (0.46) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9762260 | 0.70 | ALDH1A1 (0.41) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9762512 | 0.70 | ALDH1A1 (0.41) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9761232 | 0.69 | KMT2A (0.50) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11326258 | 0.69 | ALDH1A1 (0.37) | MAPTGAAL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL10781893 | 0.69 | ALDH1A1 (0.43) | MAPTGAAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11212059 | 0.68 | MAPT (0.37) | MAPTGAAALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |