Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969129 | 0.83 | LOXL2 (0.54) | TAAR1HTR2ACYP2A6LOXL2HRH1 | |
| SCHEMBL2011886 | 0.82 | TAAR1 (0.60) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL6546083 | 0.82 | HTR2A (0.50) | TAAR1HTR2A | |
| SCHEMBL28059422 | 0.81 | MAOA (0.46) | TAAR1CYP2A6MAOAMAOB | |
| Phenethylamine SCHEMBL3135462 | 0.80 | TAAR1 (0.64) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL717640 | 0.79 | TAAR1 (0.56) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL13557873 | 0.79 | TAAR1 (0.56) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL6547609 | 0.78 | HTR2A (0.60) | HTR2ASMN1; SMN2 | |
| Phenethylamine SCHEMBL1930179 | 0.78 | TAAR1 (0.73) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 | |
| SCHEMBL27220940 | 0.78 | TAAR1 (0.50) | TAAR1HTR2ACYP2A6SMN1; SMN2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |