SCHEMBL9762284 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	2/20	0.35

▸	RAB9A	P51151	2/20	0.33

▸	MAPT	P10636	2/20	0.33

▸	NPC1	O15118	1/20	0.33

▸	HTT	P42858	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	MAPK1	P28482	1/20	0.30

▸	L3MBTL1	Q9Y468	1/20	0.30

▸	APOBEC3G	Q9HC16	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9762325	0.77	ALDH1A1 (0.33)	ALDH1A1MAPTL3MBTL1
SCHEMBL10420191	0.71	DYRK1A (0.42)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL14295795	0.70	MAPT (0.35)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL9761190	0.68	TSHR (0.37)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL25792266	0.68	MAPT (0.40)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL9761080	0.67	MAT2A (0.34)	ALDH1A1RAB9AMAPTHTT
SCHEMBL9761821	0.67	ALDH1A1 (0.42)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL9124018	0.66	TDP1 (0.38)	ALDH1A1RAB9AMAPTNPC1HTT
SCHEMBL9762410	0.66	ALOX15 (0.42)	ALDH1A1RAB9AMAPTSMN1; SMN2
SCHEMBL9762532	0.64	ALDH1A1 (0.31)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5026694-A	Antitumor agents	THE BRITISH COLUMBIA CANCER FOUNDATION (CA)	1991-06-25	—	—	US	disclosed